#523 Hotcakes: Left Atrial Appendage Closure vs AC for Afib, Apixaban vs Rivaroxaban for VTE, Intensive LDL Targeting, GLP1s and Substance Use Disorders, and more
4/27/20261 hr 6 min
Join us as we review recent practice-changing articles on left atrial appendage closure vs AC for AFib, apixaban vs rivaroxaban for VTE, intensive LDL targeting, GLP1s and substance use disorders, and more! Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Shani Herzig (@ShaniHerzig) Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto).
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Credits
- Written and Hosted by: Rahul Ganatra MD, MPH; Shani Herzig, MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP
- Cover Art: Rahul Ganatra MD, MPH
- Reviewer: Emi Okamoto, MD
- Technical Production: Pod Paste
- Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Show Segments
- Intro, disclaimer
- Left atrial appendage closure vs anticoagulation in AF
- Apixaban vs rivaroxaban for VTE
- Intensive LDL targeting in ASCVD
- GLP1s and substance use disorders
- FDA approves Orforglipron
- E-cigarettes and cancer
- Early AM blood draws and sleep quality
- Outro
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Clips
Showing 10 of 14Transcript preview
First 90 secondsMatthew Watto· Host0:00
It's 2026, and we're about to have our three-year anniversary of our Patreon at patreon.com/curbsiders. So to celebrate, we're offering the first 1,000 members who sign up free house officer privileges for one month. That lets you get access to 70-plus bonus episodes where Paul and I recap high-yield pearls, answer listener questions, and give our picks of the week. It's a lot of fun, so check us out at patreon.com/curbsiders, or you can click the link in the episode description to sign up. [electronic beeping] Paul?
Paul Williams· Host0:33
What up?
Matthew Watto· Host0:35
The guy who stole my diary has gone missing.
Paul Williams· Host0:38
Yeah, I can't get there.
Matthew Watto· Host0:44
My thoughts are with his family, Paul.
Paul Williams· Host0:46
[laughs] That's a great one.
Matthew Watto· Host0:49
[laughs] Thank you.
Paul Williams· Host0:51
That might be one of the better ones you've done. That's pretty good.
Matthew Watto· Host0:52
That was from countryliving.com, uh, under the dark dad jokes section.
Paul Williams· Host0:56
[laughs] [laughs] I loved it.
Speaker 20:59
[upbeat music] The Curbsiders Podcast is for entertainment, education, and information purposes only, and the topics discussed should not be used solely to diagnose, treat, cure, or prevent any diseases or conditions. Furthermore, the views and statements expressed on this podcast are solely those of those and should not be interpreted to reflect official policy or position of any entity, aside from possibly Cash-Acorn Hospital and its affiliate outreach programs, if indeed there are any. In fact, there are none. Pretty much, we aren't responsible if you screw up. You should always do your own homework and let us know when we're wrong.
Matthew Watto· Host1:20
[electronic beeping] [static] [upbeat music] Welcome back to The Curbsiders. I'm Dr. Matthew Frank Wado, here with