The Peter Attia Drive#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.Why ApoE4 Raises Alzheimer’s Risk
58:52–1:00:30 · 98s
Tom explains how the ApoE4 variant creates dysfunctional brain HDL, starves neurons of cholesterol, and accelerates amyloid-tau production—clarifying the genetic link to Alzheimer’s.