Locking Peptide Boosts Affinity
14:37–16:14 · 97s
Rob reveals how constraining a floppy macrocyclic peptide’s conformation—trading entropy for tighter binding—supercharged its potency against PCSK9.
14:37–16:14 · 97s
Rob reveals how constraining a floppy macrocyclic peptide’s conformation—trading entropy for tighter binding—supercharged its potency against PCSK9.
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