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Pope vs AI, Anthropic's Digital God, AI Job Loss Narrative Flips, Open Source Crackdown Coming?

5/29/20261 hr 35 min

(0:00) Bill Gurley joins the show!

(6:00) Making yourself valuable in the age of AI, first class of "AI Natives"

(17:37) Reacting to Pope Leo's AI encyclical: Who guards the guardians?

(26:54) Anthropic's Digital God: Do they believe they are creating a superior species?

(38:32) AI sovereignty, the next era of privacy, open-source crackdown coming?

(59:56) The Great AI Jobs Debate: Dario and Sam Altman flip their rhetoric, Goldman CEO says no AI job apocalypse

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Intro Music Credit:

https://rb.gy/tppkzl

https://x.com/yung_spielburg

Intro Video Credit:

https://x.com/TheZachEffect

Referenced in the show:

https://www.vatican.va/content/leo-xiv/en/encyclicals/documents/20260515-magnifica-humanitas.html

https://www.youtube.com/watch?v=ORFrdYSvzuw

https://rdad.org

https://www-cdn.anthropic.com/9214f02e82c4489fb6cf45441d448a1ecd1a3aca/claudes-constitution.pdf

https://www.youtube.com/watch?v=0GaKJ4Fp2x4

https://allpoetry.com/All-Watched-Over-By-Machines-Of-Loving-Grace

https://darioamodei.com/essay/machines-of-loving-grace

https://x.com/chamath/status/2059850242779136031

https://x.com/vivekgaripalli/status/2059651390784344491

https://x.com/edzitron/status/2059122774401311095

https://p3institute.substack.com/p/from-open-source-software-to-open

https://www.theinformation.com/newsletters/the-briefing/anthropic-likely-generating-least-35-revenue-openai

https://www.theverge.com/tech/930447/microsoft-claude-code-discontinued-notepad

https://x.com/Polymarket/status/2060034216906068131

https://x.com/savipww/status/2060070450785305030

https://www.nytimes.com/2026/05/22/opinion/ai-job-crisis-goldman-sachs.html

https://fortune.com/2026/05/26/sam-altman-dario-amodei-walking-back-ai-jobs-apocalypse-prophecies-ipo

https://fortune.com/2026/05/05/dario-amodei-jevons-paradox-will-ai-wipe-out-white-collar-jobs

https://www.entrepreneur.com/business-news/jack-dorseys-block-cuts-4000-jobs-critics-claim/503108

Clips

Transcript preview

First 90 seconds
  1. Jason Calacanis· Host0:00

    Okay, we are gathered here today- [laughs] ... in holy unity, brothers and sisters, to convene and discuss on this most holy day, the day the All-In podcast drops, many topics: AI data centers, China, justice, human dignity. Dario unwinding these SPVs hasn't been good for the Vatican. [laughs] We got in at 20 billion. That was a 50-bagger for us. So let's get started.

  2. Chamath Palihapitiya· Host0:32

    Jason, I'm pretty sure you believed you were the vicar of God before the encyclical, so this is nothing new for you. [upbeat music] [laughs] You let your winners ride.

  3. Bill Gurley· Guest0:42

    Rain Man David Sacks.

  4. David Sacks· Host0:46

    I'm going all in.

  5. Jason Calacanis· Host0:48

    And instead- We open sourced it to the fans, and they've just gone crazy with it.

  6. Bill Gurley· Guest0:52

    Love you, S.

  7. Jason Calacanis· Host0:53

    I think queen of quinoa.

  8. David Sacks· Host0:54

    I'm going all in.

  9. Jason Calacanis· Host0:56

    The smoke has risen from Chamath's pool house. [laughs] And from the poker room.

  10. Chamath Palihapitiya· Host1:04

    He's staying in my pool house. He's been there for the last three days.

  11. Jason Calacanis· Host1:06

    It's been magnificent. He didn't know. You know what? I understand where OJ was coming from. [laughs] You know, you put Kato Kaelin in your house for long enough, you just lose your [beep] at some, at some point. [laughs] Somebody's getting whacked. All right, enough with the shenanigans. Uh, but it's been great staying at the house because there's actually, Chamath is not aware of this, there's an iPad in the kitchen, and that's logged

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