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OpenAI’s Big Reset + A.I. in the Doctor’s Office + Talkie, a pre-1930s LLM

5/1/20261 hr 10 min

This week, OpenAI announced a loosened partnership with Microsoft and an aggressive new strategy to secure computing power. We unpack what these updates signal about OpenAI’s business strategy and whether the company can scale while balancing a trial against Elon Musk and investor concerns over missed financial targets. Then, the A.I. researcher Dr. Adam Rodman, of Harvard Medical School, returns to tell us about the most significant ways A.I. is changing how doctors treat patients. And finally, can an LLM trained only on very old texts predict the future? We’re talking with one of the creators of the chatbot talkie.

 

Guests:

  • Dr. Adam Rodman, internal medicine physician at Beth Israel Deaconess Medical Center and assistant professor at Harvard Medical School.
  • David Duvenaud, associate professor at the University of Toronto, former team lead at Anthropic and co-creator of talkie.

 

Additional Reading:

 

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Clips

Transcript preview

First 90 seconds
  1. Speaker 00:00

    Maybe that's an urgent message from your CEO, or maybe it's a deep fake trying to target your business. Doppel is the AI-native social engineering defense platform fighting back against impersonation and manipulation. As attackers use AI to make their tactics more sophisticated, Doppel uses it to fight back. From automatically dismantling cross-channel attacks to building team resilience and more, Doppel, outpacing what's next in social engineering. Learn more at doppel.com. That's D-O-P-P-E-L.com.

  2. Kevin Roose· Host0:31

    Casey, I miss you. You are in New York?

  3. Casey Newton· Host0:34

    I am, Kevin, and of course I miss you as well, but it's always fun to visit the mothership. You know, uh, Ezra Klein just challenged me to a burping contest- [laughs] So I've got that to look forward to later.

  4. Kevin Roose· Host0:45

    Burping or burpee?

  5. Casey Newton· Host0:47

    [laughs] Um, you know what? I guess I should go read that email again.

  6. Kevin Roose· Host0:50

    [laughs] Okay. Well, I miss you. We have an empty chair here in San Francisco, um, and it's not the same.

  7. Casey Newton· Host0:57

    It's not the same, but I've been catching up on all the latest AI news, Kevin, and I, I had to ask: Have you seen this thing about, uh, Codex and the goblins?

  8. Kevin Roose· Host1:05

    Uh, yes. This is the new update to OpenAI's Codex that is, like, obsessed with goblins?

  9. Casey Newton· Host1:11

    Yes. Uh, apparently, the company had to add s- instructions to its latest model to forbid Codex from randomly mentioning an assortment of mythical and real creatures, including goblins, gremlins, raccoons, trolls, ogres, and pigeons.

  10. Kevin Roose· Host1:26

    Or, as we call them, our slate of guests- [laughs]

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