Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017
7/8/202621 min
In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for microplastic toxicity.
From the autonomic anxiety caused by biological lockdown to the clinical application of precision metabolomics, this roundtable shifts the conversation from invasive procedures to measurable, cellular safety signals.
Join us as we delve into:
- The Protein Corona: How circulating microplastics masquerade as pathogens, triggering localized purinergic signaling and the release of extracellular ATP.
- The Cell Danger Response (CDR1): Why the body halts oxidative phosphorylation and locks down the cell membrane when invaded, and why blood washing can't touch toxins stuck inside tissue matrices.
- The Problem with Plasmapheresis: The clinical realities and physiological costs of invasive vascular filtering, including the removal of essential immunoglobulins and clotting factors.
- The True Detox Protocol: Utilizing organic carbon binders (humic and fulvic acids), phase two liver conjugation (glucuronidation/sulfation), and barrier integrity support to properly excrete microplastics.
- Pulsed Antioxidant Support: When and why to use targeted NAD, alpha-lipoic acid, NAC, and ubiquinol to transition cells out of a defensive lockdown.
This episode is for you if:
- You are considering expensive therapies like plasmapheresis to clear environmental toxins.
- You want to learn how to test your cellular metabolomics for organic acids and brain inflammation.
- You want to understand how your unique exposome interacts with your cellular safety mechanisms.
You can also find this episode on…
YouTube: https://youtu.be/5b4jWqByRAU
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Clips
Transcript preview
First 90 secondsTed Achacoso· Host0:00
Over 80% of human blood tested now contains circulating microplastics and nanoplastics, including sperm. These aren't just inert debris. They actively bind to our plasma proteins and accumulate in our tissue matrices. Many people are turning to invasive vascular filtering, like plasmapheresis, to wash their blood. But blood washing alone cannot touch plastic locked inside your cells. True detox requires cellular safety, not just mechanical filtering.
Scott Sherr· Host0:30
Welcome to the Health Optimization Medicine podcast. Your clinical team here today is Dr. Alan Bucats, chief of emergency medicine; Dr. Ted Achacoso, founder of Health Optimization Medicine and Practice; Jodi Duvall, naturopathic doctor; Boomer Anderson, CEO and homope practitioner; and myself, Dr. Scott Sherr, a board-certified internist. Today, your clinical team is going after one question: Can you wash microplastics out of your blood? In the next 25 minutes, you're going to get the cellular mechanism, the clinical protocol, and the one thing most practitioners get completely wrong about environmental detox. Let's go.
Boomer Anderson· Host1:07
All right, this is a juicy one, or maybe a little bit of a plasticky one, guys. So let's get into the clini- clinical question of the day right on the table right now. And it-- Right, given this moment, there's been an absolute explosion of marketing around therapeutic plasma exchange.
Scott Sherr· Host1:23
So much, yeah.
Boomer Anderson· Host1:23
How many of us have done it? Anybody here?
Scott Sherr· Host1:25
No, I haven't done it yet.
Ted Achacoso· Host1:26
I want to do it.
Boomer Anderson· Host1:26
Nope. I do kind of want to do-- Yeah, I want to do it, but, like,

