#428: Poop, Peptides & The Power of Microbiome | The Secret Longevity Organ With Dr. Grace Liu
4/10/20261 hr 25 min
Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself. Episode Timestamps: Introduction to host ... 00:00:00 Dr. Grace Liu on the gut as a hallmark of aging ... 00:04:06 Peptides, FMT, and evidence for gut-driven regeneration ... 00:05:04 FMT safety, immune education, and the environmental “microdosing” effect ... 00:07:07 Links between gut aging, the immune system, and mental health ... 00:08:13 Diet, ancestry, and resistant starch for butyrate production ... 00:15:01 Ancestral diet, microbiome differences, and pitfalls of shortcuts ... 00:18:53 Fiber, polyphenols, and the key longevity bacteria ... 00:24:09 Gut markers, loss of diversity, and ABC species signature ... 00:25:15 Risks of overhyped probiotics, strep, and broad interventions ... 00:36:29 Peptides, bioregulators, and repairing the gut ... 01:12:01 Practical longevity: movement, daily habits & where to learn more ... 01:22:46 Our Amazing Sponsors: Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. CP1 Pure Collagen Peptides by Puori — a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus full third-party testing; go to puori.com/NAT and use code NAT for 32% off when you start a subscription. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode
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First 90 secondsNathalie Niddam· Host0:00
[outro music] Welcome to Longevity. I'm your host, Natalie Needham. I'm a nutritionist, a human potential and epigenetic coach, and I created this podcast to bring you the latest ways to take control of your health and longevity. We cover it all, from new technology and ancestral health practices to personalized interventions, and a very special interest of mine, peptides and bioregulators. Enjoy the show. Welcome to the show, folks. I'm Natalie Needham, your host. Today's episode starts with a sentence I never thought I'd really say on this podcast. Poop might be one of the most powerful longevity tools in our possession. Dr. Grace Liu is back, and we're unpacking the idea that your gut isn't just about digestion. It is literally shaping your immune system, your brain development, your lifespan, and your health span. We talk about the surprising science behind fecal transplants and how they've been shown to extend lifespan in animal models, why your gut bacteria are training your brain from birth, and how modern life, from antibiotics to ultra-clean environments, is quietly wrecking your microbiome. Now, you may have heard of Dr. Grace Liu before as the Gut Goddess, and she still is. She is the founder of The Gut Institute, where she markets some incredibly powerful tools to address microbiome imbalances. Now, if you wanna check them out and some of Dr. Grace's signature probiotic blends, we have a link in the show notes